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Cagent Vascular Raises $30 Million Series C Financing
Funds will be used to accelerate US market adoption and to expand the product portfolio of the first and only Serration Angioplasty Technology
(Wayne, PA) Cagent Vascular, Inc., a rapidly growing commercial stage medical device company, today announced a Series C Financing close in excess of $30M. U.S. Venture Partners (USVP), led the round. Participation included new investor Blue Ridge Medical, LLC and existing investors, including Sectoral Asset Management.
“We are pleased with the significant investment from U.S. Venture Partners and other new and existing investors. To date, we estimate that over 10,000 Serranator PTA Serration Balloon Catheters (Serranator) have been used to treat those suffering from Peripheral Artery Disease (PAD). This infusion of capital will increase our commercial reach, helping to provide greater access for healthcare providers and their patients,” stated Carol A. Burns, CEO.
USVP is a leading Silicon Valley venture capital firm in Menlo Park, CA. “At US Venture Partners, we understand the challenges facing PAD patients and are keenly aware of the need for innovation for this vulnerable patient population. As we reviewed the impressive clinical data and spoke to physicians about their patient outcomes, it was clear that Serration Angioplasty is truly innovative. This was further underscored by the strong early commercial success driven by the exceptional team at Cagent Vascular,” said Casey Tansey, General Partner, US Venture Partners.
The Serranator PTA Serration Balloon Catheter (Serranator) has three embedded serrated elements designed to modify the plaque by creating linear, interrupted scoring along the endoluminal surface to aid arterial expansion. The Serranator’s unique mechanism of action has demonstrated greater lumen gain than plain angioplasty balloons. Increased lumen gain results in restored blood flow to the foot, leading to wound healing and relief of symptoms.
A recently published study in the Journal of Endovascular Therapy compared the degree of elastic recoil, a dramatic loss of lumen gain that occurs within 15 minutes of treatment, in Serranator-treated versus plain balloon in below-the-knee lesions. These unique results demonstrated 55% mean elastic recoil in the plain balloon group versus just 6% in the Serranator group. These data indicate a potential significant improvement for people with Chronic Limb Threatening Ischemia (CLTI), the most advanced stage of peripheral artery disease (PAD), where arteries are prone to elastic recoil post- treatment, reducing blood flow.
The Serranator has received FDA 510k Clearance and is intended for dilatation of lesions in the iliac, femoral, iliofemoral, popliteal and infrapopliteal arteries for the treatment of obstructive lesions of native or synthetic arteriovenous dialysis fistulae. The product is currently being sold in the US. The Serranator device also has CE Mark and limited distribution in Europe.
About Cagent Vascular
Cagent Vascular, founded and led by serial medical technology entrepreneurs, is the leader in Serration Technology to treat peripheral artery disease. The company has developed a transformative improvement to conventional angioplasty, which is the most commonly performed procedure to restore blood flow. Although angioplasty has been used clinically for over 50 years, there remain significant opportunities to optimize the therapy and to improve the treatment outcomes of cardiovascular disease. To learn more about how Cagent Vascular’s mission to fight PAD visit www.cagentvascular.com.
The information contained herein obtained from Cagent Vascular management is believed to be reliable. This does not constitute the solicitation of the purchase or sale of securities. Except for historical information contained herein, matters discussed in this document are forward-looking statements, the accuracy of which is subject to risks and uncertainties.
Contact: Lauren Pfeiffer at 610.688.2006 or [email protected]
This project is supported by the Ben Franklin Technology Partners of Southeastern PA, an initiative of the Pennsylvania Department of Community and Economic Development funded by the Ben Franklin Technology Development Authority.
 Fereydooni A, Chandra V, Schneider PA, Giasolli R, Lichtenberg M, Stahlhoff S. J Endovasc Ther. 2023 Dec 7
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