Serranator with Drug-Coated Balloons
Multiple physicians
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In the above-the-knee population, I see this as a very useful device. I’m a strong user of drug-eluting technologies.
If you use a Serranator balloon in an above-the-knee lesion and create micro-serrations, you could potentially achieve better drug uptake from a drug-coated balloon and ultimately improve long-term outcomes.
In my practice, my algorithm has already changed with Serranator. In above-the-knee, heavily calcified lesions—particularly those with grade D circumferential calcium—we know there is poor drug uptake following plain balloon angioplasty.
However, by using Serranator technology to create controlled intimal penetrations and then following with drug-coated balloon angioplasty, I believe we can achieve better drug uptake and delivery.
We know that for drug therapies to work effectively, we need deep plaque penetration into the medial layer of the vessel. To accomplish that, we need controlled plaque disruption—but in a way that avoids dissection.
I believe Serranator technology is uniquely positioned to do this effectively.
Plaque modification is critical, especially when trying to expose as much smooth muscle as possible for optimal drug absorption. That’s why we have so many tools in our armamentarium designed to modify plaque.
Serranator is a highly effective tool for plaque modification through angioplasty, allowing you to potentially optimize or improve drug uptake—which is the final step in treating these patients with stenosis.
